<p><strong>About The Study: </strong>In a multicenter observational cohort, a composite adverse pregnancy outcome (small-for-gestational-age birth, medically indicated preterm birth, stillbirth, or hypertensive disorders of pregnancy) was more frequent in pregnant individuals with cannabis exposure ascertained by a urine drug assay compared with unexposed individuals. The risk for an adverse outcome was higher among those who continued to use cannabis beyond the first trimester.<strong> </strong></p>