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Vital cystic fibrosis drug and HRT among medications people have struggled to find, as shortages become ‘new normal’ in UK
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Nursery worker Kate Roughley, 37, accused of manslaughter over death of Genevieve Meehan in May 2022
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Police believe attack on dissident journalist was latest example of Tehran hiring criminal proxies to assault its critics in west
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Letters: Norma Neill and Judith A Daniels respond to a Guardian leader on the long path to enlightenment
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The prime minister has faced opposition from some Tory MPs over a law to ban people born after 2009 from buying tobacco
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Editorial: Fresh allegations against a backbench MP highlight an end-of-era atmosphere in the Conservative party
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Mayor says ‘brand Andy’ move is utterly deliberate as people are ‘sick and tired of Westminster’
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Homes, barns, trees and power lines were all damaged as storms hit on Tuesday
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Tensions between Israel and Iran have reached new heights as Tehran repeats its warnings that a response to its own missile attack could be lethal for the region
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Jury selection in Donald Trump's hush money trial has encountered new setbacks as a previously seated juror was excused after backtracking on whether she felt she could be impartial and fair
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Officers found a DNA match for suspect Raul Meza Jr in 2020, but he wasn’t arrested until 2023
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Katherine Altagracia Guerrero De Aguasvivas, 31, was found dead after a brazen carjacking and now, a Florida sheriff says new details linking it to another murder are ‘right out of a television show’. Andrea Cavallier reports
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Watch live as Joe Biden holds a campaign rally in Philadelphia, where more than 15 members of the Kennedy political family are expected to endorse his campaign for re-election.
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Most of Captain Everett Leland Yager’s remains were recovered in Riverside County, California after the 1951
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Congresswoman Omar had previously expressed her support for the protests at Columbia
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Moises Tejada, 54, was picked up in St Peter’s Square near the Vatican last week, and found to be carrying three concealed knives
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Scientists estimate Vasuki indicus was up to 15m long, weighed a tonne and would have constricted its prey
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Tentative offer follows four months of talks and could create new banking group with almost 5m customers
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Exclusive: Project Timber could see some lenders lose up to 40% of their money under the plans
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Kristalina Georgieva says Kyiv will need $42bn of financial support this year as G7 considers ways to use seized Russian assets
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